1FM9 -结合位点数据库

PDB ID: 1FM9

中文名称:过氧化物酶体增殖物活化受体γ

英文名称:Peroxisome proliferator-activated receptor gamma

相关疾病:糖尿病

相关虚拟筛选等药物设计文章:

[1]Murugan R, Anbazhagan S, Lingeshwaran, Sriman Narayanan S. Synthesis and in vivo antidiabetic activity of novel dispiropyrrolidines through [3+2] cycloaddition reactions with thiazolidinedione and rhodanine derivatives. Eur J Med Chem. 2009 Aug;44(8):3272-9.DOI: 10.1016/j.ejmech.2009.03.035.

[2]Guasch, L.; Sala, E.; Castell-Auví, A.; Cedó, L.; Liedl, K. R. PLOS ONE: Identification of PPARgamma Partial Agonists of Natural Origin (I): Development of a Virtual Screening Procedure and in Vitro Validation. PloS one 2012. DOI:10.1371/journal.pone.0050816

Site ID: 2

Deposition Date: 2000-08-16

Experiment Method: XRay

Chains ID: D

Uniprot ID: PPARG_HUMAN

Uniprot Name: Peroxisome proliferator-activated receptor gamma

Uniprot AC: P37231

Species Reign: Homo sapiens

HET Code:570

AutoDock Vina Search Space.

Please copy and save it as VINA configuration file.

center_x = 12.0955
center_y = -6.69688
center_z = 9.07366
size_x = 15
size_y = 15
size_z = 15

Binding Mode

Binding Site Cluster ID: C-0025-1

Click here to download the cluster: C-0025.tar.gz

Click here to download protein file(ready for docking): 1fm9_protein.mol2.gz

Click here to download ligand file(ready for docking): 1fm9_ligand.mol2.gz

Click here to download PDBQT file(ready for AutoDock VINA): 1fm9 protien.pdbqt.gz